wiscstatman/MixTwice: MixTwice--a package for large-scale hypothesis testing

MixTwice is a R package for large-scale hypothesis testing. It takes two statistics per testing unit -- an estimated effect and its associated squared standard error -- and fits a nonparametric, shape-constrained mixture separately on two latent parameters. It reports local false discovery rates (lfdr) and local false sign rates (lfsr).

install.packages("remotes")
remotes::install_github("wiscstatman/MixTwice")