zhouzilu/cTPnet: Single cell Transcriptome to Protein prediction with deep neural network (cTP-net)

While single cell RNA sequencing (scRNA-seq) is invaluable for studying cell populations, cell-surface proteins are often integral markers of cellular function and serve as primary targets for therapeutic intervention. Here we propose a transfer learning framework, single cell Transcriptome to Protein prediction with deep neural network (cTP-net), to impute surface protein abundances from scRNA-seq data by learning from existing single-cell multi-omic resources.

Getting started

Package details

AuthorZilu Zhou (zhouzilu@pennmedicine.upenn.edu), Nancy R. Zhang (nzh@wharton.upenn.edu)
MaintainerZilu Zhou <zhouzilu@pennmedicine.upenn.edu>
LicenseGPL-3
Version1.0.3
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("zhouzilu/cTPnet")
zhouzilu/cTPnet documentation built on July 13, 2022, 2:54 a.m.