The package provides tools to model and test the association between multiple genotypes and multiple traits, taking into account the prior biological knowledge. Genes, and clinical pathways are incorporated in the model as latent variables. The method is based on Generalized Structured Component Analysis (GSCA).
|Author||Hela Romdhani, Stepan Grinek , Heungsun Hwang and Aurelie Labbe.|
|Date of publication||None|
|Maintainer||Hela Romdhani <firstname.lastname@example.org>|
ASGSCA-package: Association Studies for multiple SNPs and multiple traits...
B0: Matrix indicating connections between the latent variables...
GenPhen: Dataset to test GSCAestim and GSCA functions.
GSCA: Association test for multiple genotypes and multiple traits...
GSCAestim: Structural Equation Models for multiple genotypes and...
QCAHS: Dataset used in the vignette.
ResQCAHS: A list containing the results obtained for the QCAHS dataset.
W0: Matrix indicating connections between the observed variables...
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