DNABarcodeCompatibility-package: DNABarcodeCompatibility: to find optimised sets of compatible...

Description

Description

The DNABarcodeCompatibility package provides six functions to load DNA barcodes, and to generate, filter and optimise sets of barcode combinations for multiplex sequencing experiments. In particular, barcode combinations are selected to be compatible with respect to Illumina chemistry constraints, and can be filtered to keep those that are robust against substitution and insertion/deletion errors thereby facilitating the demultiplexing step. In addition, the package provides an optimiser function to further favor the selection of compatible barcode combinations with least heterogeneity in barcode usage.


DNABarcodeCompatibility documentation built on Nov. 8, 2020, 5:36 p.m.