DNABarcodeCompatibility-package: DNABarcodeCompatibility: to find optimised sets of compatible...
In DNABarcodeCompatibility: A Tool for Optimizing Combinations of DNA Barcodes Used in Multiplexed Experiments on Next Generation Sequencing Platforms
Description
The DNABarcodeCompatibility package provides six functions to load DNA
barcodes, and to generate, filter and optimise sets of barcode combinations
for multiplex sequencing experiments.
In particular, barcode combinations are selected to be compatible with
respect to Illumina chemistry constraints, and can be filtered to keep those
that are robust against substitution and insertion/deletion errors
thereby facilitating the demultiplexing step.
In addition, the package provides an optimiser function to further favor
the selection of compatible barcode combinations with least
heterogeneity in barcode usage.
DNABarcodeCompatibility documentation built on Nov. 8, 2020, 5:36 p.m.
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Description
The DNABarcodeCompatibility package provides six functions to load DNA barcodes, and to generate, filter and optimise sets of barcode combinations for multiplex sequencing experiments. In particular, barcode combinations are selected to be compatible with respect to Illumina chemistry constraints, and can be filtered to keep those that are robust against substitution and insertion/deletion errors thereby facilitating the demultiplexing step. In addition, the package provides an optimiser function to further favor the selection of compatible barcode combinations with least heterogeneity in barcode usage.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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