DNaseR: DNase I footprinting analysis of DNase-seq data

Strand-specific digital genomic footprinting in DNase-seq data. The cumulative Skellam distribution function (package 'skellam') is used to detect significant normalized count differences of opposed sign at each DNA strand. This is done in order to determine the protein-binding footprint flanks. Preprocessing of the mapped reads is recommended before running DNaseR (e.g., quality checking and removal of sequence-specific bias).

Package details

AuthorPedro Madrigal <[email protected]>
MaintainerPedro Madrigal <[email protected]>
LicenseGPL-2 + file LICENSE
Package repositoryView on Bioconductor
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DNaseR documentation built on Sept. 12, 2016, 6:05 a.m.