Combine Profiles

Description

Combine a set of hybridisations using the median rank method as proposed by Warnat

Usage

1

Arguments

data

A list of R objects, each object should contain a matrix of expression values to be merged with each other. The first object will be used as the reference data set.

Details

The combine profiles function merges a set of expression values, normalising across different experiments to facilitate the meta-analysis of similar experiments i.e. cell lines treated with the same drug but which may be from different "batches" or platforms.

Value

Matrix of rank normalised expression data. Rows are genes, columns are hybridisations from the different experiments.

Author(s)

C. Pacini

References

R code from CONOR package. Need also reference to the method.