This package gives the implementations of the gene expression signature and its distance to each. Gene expression signature is represented as a list of genes whose expression is correlated with a biological state of interest. And its distance is defined using a nonparametric, rank-based pattern-matching strategy based on the Kolmogorov-Smirnov statistic. Gene expression signature and its distance can be used to detect similarities among the signatures of drugs, diseases, and biological states of interest.
|Date of publication||None|
|Maintainer||Yang Cao <email@example.com>, Fei Li <firstname.lastname@example.org>,Lu Han <email@example.com>|
exampleSet: sample data, a subset of the C-MAP
GeneExpressionSignature: Introduction to the GeneExpressionSignature Package
getRLs: Convert gene expression profiles to a ranked list (data...
RankMerging: Merging the ranker lists with the same labels of the...
ScoreGSEA: Compute pairwise distances between samples with method in...
ScorePGSEA: Compute pairwise distances between samples with method in...
SignatureDistance: Compute pairwise distances comprehensively.
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