Ig: IGHV gene family usage in vaccine-challenged B-cell...

In IgGeneUsage: Differential gene usage in immune repertoires

Description

A small example database subset from study evaluating vaccine-induced changes in B-cell populations publicly provided by R-package alakazam (version 0.2.11). It contains IGHV gene family usage, reported in four B-cell populations (samples IgM, IgD, IgG and IgA) across two timepoints (conditions = -1 hour and +7 days).

Usage

data("Ig")

Format

A data frame with 4 columns: "sample_id", "condition", "gene_name" and "gene_usage_count". The format of the data is suitible to be used as input in IgGeneUsage

Source

R package: alakazam version 0.2.11

References

Laserson U and Vigneault F, et al. High-resolution antibody dynamics of vaccine-induced immune responses. Proc Natl Acad Sci USA. 2014 111:4928-33.

Examples

data(Ig)
head(Ig)

IgGeneUsage documentation built on Nov. 8, 2020, 7:47 p.m.