POST-package: Projection onto Orthogonal Space Testing for High Dimensional...
In POST: Projection onto Orthogonal Space Testing for High Dimensional Data

Description Details Author(s) References Examples

a tool to indentify gene sets that are associated with a endpoint of interest by projecting the original data of a set to an orthogonal subspace.

Package:	POST
Type:	Package
Version:	0.99.3
Date:	2016-11-2
License:	GPL (>=2)
LazyLoad:	yes

The POST (Projection onto Orthogonal Space Testing) is performed by calling function POSTglm for linear model or POSTcoxph for Cox proportional hazard model. The genomic data such as gene expression is passed through ExpressionSet; The gene set definition is defined by a gene set collection.

Xueyuan Cao Xueyuan.cao@stjude.org, Stanley Pounds stanley.pounds@stjude.org

Maintainer: Xueyuan Cao xueyuan.cao@stjude.org

Hotelling H. (1936). Relations between two sets of variables. Biometrika, 28, 321-327

 ## load data
 data(sampExprSet)
 data(sampGeneSet)
 test<-POSTglm(exprSet=sampExprSet,                         
               geneSet=sampGeneSet,                         
               lamda=0.95,                      
               seed=13,                        
               nboots=100,                      
               model='Group ~ ',   
               family=binomial(link = "logit"))