Polyfit: Add-on to DESeq to improve p-values and q-values

Polyfit is an add-on to the packages DESeq which ensures the p-value distribution is uniform over the interval [0, 1] for data satisfying the null hypothesis of no differential expression, and uses an adpated Storey-Tibshiran method to calculate q-values.

Package details

AuthorConrad Burden
Bioconductor views DifferentialExpression GeneExpression ImmunoOncology RNASeq Sequencing
MaintainerConrad Burden <conrad.burden@anu.edu.au>
LicenseGPL (>= 3)
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))


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Polyfit documentation built on Nov. 8, 2020, 5:26 p.m.