RnaSeqSampleSize: RnaSeqSampleSize

RnaSeqSampleSize package provides a sample size calculation method based on negative binomial model and the exact test for assessing differential expression analysis of RNA-seq data. It controls FDR for multiple testing and utilizes the average read count and dispersion distributions from real data to estimate a more reliable sample size. It is also equipped with several unique features, including estimation for interested genes or pathway, power curve visualization, and parameter optimization.

Package details

AuthorShilin Zhao Developer [aut, cre], Chung-I Li Developer [aut], Yan Guo Developer [aut], Quanhu Sheng Developer [aut], Yu Shyr Developer [aut]
Bioconductor views DifferentialExpression ExperimentalDesign GeneExpression ImmunoOncology RNASeq Sequencing
MaintainerShilin Zhao Developer <zhaoshilin@gmail.com>
LicenseGPL (>= 2)
Version2.0.0
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RnaSeqSampleSize")

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RnaSeqSampleSize documentation built on Nov. 8, 2020, 6:54 p.m.