The aim of XINA is to determine which proteins exhibit similar patterns within and across experimental conditions, since proteins with co-abundance patterns may have common molecular functions. XINA imports multiple datasets, tags dataset in silico, and combines the data for subsequent subgrouping into multiple clusters. The result is a single output depicting the variation across all conditions. XINA, not only extracts coabundance profiles within and across experiments, but also incorporates protein-protein interaction databases and integrative resources such as KEGG to infer interactors and molecular functions, respectively, and produces intuitive graphical outputs.
Package details |
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Author | Lang Ho Lee <lhlee@bwh.harvard.edu> and Sasha A. Singh <sasingh@bwh.harvard.edu> |
Bioconductor views | Network Proteomics RNASeq SystemsBiology |
Maintainer | Lang Ho Lee <lhlee@bwh.harvard.edu> and Sasha A. Singh <sasingh@bwh.harvard.edu> |
License | GPL-3 |
Version | 1.8.0 |
Package repository | View on Bioconductor |
Installation |
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