betr-package: Identify differentially expressed genes in microarray...
In betr: Identify differentially expressed genes in microarray time-course data

Description Details Author(s) References See Also Examples

The betr package implements the BETR (Bayesian Estimation of Temporal Regulation) algorithm.

Package:	betr
Type:	Package
License:	LGPL (>= 2.0)
LazyLoad:	yes

Martin Aryee Maintainer: <aryee@jhu.edu>

Smyth, G. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Statistical applications in genetics and molecular biology (2004) vol. 3, article 3 Tai, Y and Speed, T. A multivariate empirical Bayes statistic for replicated microarray time course data. Annals of Statistics (2006) vol. 34 (5) pp. 2387-2412

betr

library(Biobase)    
data(timeEset)
prob <- betr(timeEset, cond=pData(timeEset)$strain, 
    timepoint=pData(timeEset)$time, replicate=pData(timeEset)$rep, alpha=0.05)
head(prob)