get.helland.subtypes: Get ovarian cancer subtypes as defined by Helland et al.,...

Description Usage Arguments Value References Examples

View source: R/get.helland.subtypes.R

Description

Get ovarian cancer subtypes as defined by Helland et al., 2011

Usage

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get.helland.subtypes(expression.matrix, entrez.ids)

Arguments

expression.matrix

A matrix of gene expression values with rows as genes, columns as samples.

entrez.ids

A vector of Entrez Gene IDs, corresponding to the rows of expression.matrix

Value

A list with first value Helland.subtypes containing a factor of subtype names; and second value subtype.scores containing a matrix of subtype scores

References

Helland et al. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PloS one (2011).

Examples

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library(Biobase)
data(GSE14764.eset)
expression.matrix <- exprs(GSE14764.eset)
entrez.ids <- as.character(fData(GSE14764.eset)$EntrezGene.ID)
get.helland.subtypes(expression.matrix, entrez.ids)

consensusOV documentation built on Nov. 8, 2020, 7:06 p.m.