Description Usage Arguments Value

Reduces the `methytmle`

object by way of a `limma`

model with
empirical Bayes shrinkage to include only the CpG sites below the preset
p-value cutoff. INTERNAL USE ONLY.

1 | ```
limma_screen(methytmle, var_int, type, cutoff = 0.05)
``` |

`methytmle` |
An object of class |

`var_int` |
A |

`type` |
Character indicating the particular measure of DNA methylation to
be used as the observed data in the estimation procedure, either Beta
values or M-values. The data are accessed via |

`cutoff` |
Numeric indicating the p-value cutoff that defines which
sites pass through the |

An object of class `methytmle`

, that is a subset of the original
methytmle input object which has been reduced include only the relevant CpG
sites. This subset is then used to estimate VIMs.

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