The 16S data come from Koren et al. (2011) and compared the bodysites oral, gut and plaque microbial communities in patients with atherosclerosis. The data can be analysed with our mixMC module. The data include 43 samples measured on 980 OTUs.
A list containing two data sets,
and some meta data information:
data frame with 43 rows (samples) and 980 columns (OTUs). The prefiltered normalised data using Total Sum Scaling normalisation.
data frame with 43 rows (samples) and 980 columns (OTUs). The prefiltered raw count OTU data which include a 1 offset (i.e. no 0 values).
data frame with 980 rows (OTUs) and 7 columns indicating the taxonomy of each OTU.
data frame with 43 rows indicating sample meta data.
factor of length 43 indicating the bodysite with levels arterial plaque, saliva and stool.
The data are from Koren et al. (2011) who examined the link between oral,
gut and plaque microbial communities in patients with atherosclerosis and
controls. Only healthy individuals were retained in the analysis. This study
contained partially repeated measures from multiple sites including 15
unique patients samples from saliva and stool, and 13 unique patients only
sampled from arterial plaque samples and we therefore considered a non
multilevel analysis for that experimental design. After prefiltering, the
data included 973 OTU for 43 samples. We strongly recommend to use log ratio
transformations on the
data.TSS normalisd data, as implemented in the
PLS and PCA methods, see details on www.mixOmics.org/mixMC.
data.raw include a 1 offset in order to be log ratios transformed
after TSS normalisation. Consequently, the
data.TSS are TSS
data.raw. The CSS normalisation was performed on the
orignal data (including zero values)
The raw data were downloaded from the QIITA database. Filtering and normalisation described in our website www.mixOmics.org/mixMC
Lê Cao K.-A., Costello ME, Lakis VA, Bartolo, F,Chua XY, Brazeilles R, Rondeau P. MixMC: Multivariate insights into Microbial Communities. PLoS ONE, 11(8): e0160169 (2016).
Koren, O., Spor, A., Felin, J., Fak, F., Stombaugh, J., Tremaroli, V., et al.: Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proceedings of the National Academy of Sciences 108(Supplement 1), 4592-4598 (2011)
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.