The package implements two novel twin models that are able to estimate dynamic behaviour of the variance components in the classical twin models with respect to age or other covariates such as calendar year.
Maintainer: Liang He <[email protected]>
He, L., Sillanp<c3><a4><c3><a4>, M.J., Silventoinen, K., Kaprio, J. and Pitk<c3><a4>niemi, J., 2016. Estimating Modifying Effect of Age on Genetic and Environmental Variance Components in Twin Models. Genetics, 202(4), pp.1313-1328.
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# data(data_ace) # AtCtEt(data_ace$mz, data_ace$dz, mod=c('d','d','c'), knot_a = 5, knot_c = 4) # AtCtEtp(data_ace$mz, data_ace$dz, knot_a = 6, mod=c('d','l','c'))
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