NEWS.md

In ApplyPolygenicScore: Utilities for the Application of a Polygenic Score to a VCF

Unreleased

ApplyPolygenicScore 3.0.1

Added

• Added hemizygous allele handling to dosage calculation
• Added toggle to hexbinplot at sample size threshold in create.pgs.with.continuous.phenotype.plot

Changed

• Updated INDEL effect switch reporting by strand flip checker
• Updated data structuring for automated statistical analysis in apply.polygenic.score

ApplyPolygenicScore 3.0.0 (2024-12-02)

Added

• Added handling of overlapping deletion allele notation
• Added secondary PGS/VCF variant matching method using rsID after first attempt with genomic coordinates
• Added checks for rsID as an optional column in input PGS weight files
• Added functionality to assess allele matches and correct strand flips

ApplyPolygenicScore 2.0.0 (2024-07-31)

Changed

• Renamed functions starting with reserved vocabulary for S3 generic methods merge. -> combine.

ApplyPolygenicScore 1.0.0 (2024-07-25)

• First release

ApplyPolygenicScore 0.1.0 (2024-07-25)

• INITIAL FEATURES

ApplyPolygenicScore documentation built on April 4, 2025, 12:18 a.m.