leukemia: Protein levels for 68 diagnosed AML patients of subtype M2
| leukemia | R Documentation |
Protein levels for 68 diagnosed AML patients of subtype M2
Description
A dataset containing the protein expression levels of 18 proteins for 68 AML patients of subtype M2 (according to French-American-British (FAB) classification system). The 18 proteins selected are known to be involved in apoptosis and cell cycle regulation according to the KEGG database (Kanehisa et al. 2012). This is a subset of the dataset presented in Kornblau et al. (2009).
Usage
leukemia
Format
A data frame with 68 rows and 18 variables:
- AKT
AKT protein, expression level
- AKT.p308
AKT.p308 protein, expression level
- AKT.p473
AKT.p473 protein, expression level
- BAD
BAD protein, expression level
- BAD.p112
BAD.p112 protein, expression level
- BAD.p136
BAD.p136 protein, expression level
- BAD.p155
BAD.p155 protein, expression level
- BAX
BAX protein, expression level
- BCL2
BCL2 protein, expression level
- BCLXL
BCLXL protein, expression level
- CCND1
CCND1 protein, expression level
- GSK3
GSK3 protein, expression level
- GSK3.p
GSK3.p protein, expression level
- MYC
MYC protein, expression level
- PTEN
PTEN protein, expression level
- PTEN.p
PTEN.p protein, expression level
- TP53
TP53 protein, expression level
- XIAP
XIAP protein, expression level
...
Source
http://bioinformatics.mdanderson.org/Supplements/Kornblau-AML-RPPA/aml-rppa.xls
References
Kornblau, S. M., Tibes, R., Qiu, Y. H., Chen, W., Kantarjian, H. M., Andreeff, M., ... & Mills, G. B. (2009). Functional proteomic profiling of AML predicts response and survival. Blood, The Journal of the American Society of Hematology, 113(1), 154-164.
Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., & Tanabe, M. (2012). KEGG for integration and interpretation of large-scale molecular data sets. Nucleic acids research, 40(D1), D109-D114.
