BioPET: Biomarker Prognostic Enrichment Tool

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Prognostic Enrichment is a clinical trial strategy of evaluating an intervention in a patient population with a higher rate of the unwanted event than the broader patient population (R. Temple (2010) <DOI:10.1038/clpt.2010.233>). A higher event rate translates to a lower sample size for the clinical trial, which can have both practical and ethical advantages. This package is a tool to help evaluate biomarkers for prognostic enrichment of clinical trials.

Author
Jeremy Roth [cre, aut], Kathleen F. Kerr [aut], Kehao Zhu [aut]
Date of publication
2016-07-04 20:37:10
Maintainer
Jeremy Roth <jhroth@uw.edu>
License
GPL (>= 2)
Version
0.2.0

View on CRAN

Man pages

dcaData
Simulated dataset for package 'DecisionCurve'
enrichment_analysis
Prognostic Enrichment with Real Data
enrichment_simulation
Prognostic Enrichment with Simulated Data
plot_enrichment_summaries
Plotting Prognostic Enrichment Estimates

Files in this package

BioPET
BioPET/NAMESPACE
BioPET/data
BioPET/data/dcaData.rda
BioPET/R
BioPET/R/enrichment_analysis.R
BioPET/R/plot_enrichment_summaries.R
BioPET/R/data.R
BioPET/R/sample_size.R
BioPET/R/enrichment_simulation.R
BioPET/MD5
BioPET/DESCRIPTION
BioPET/man
BioPET/man/plot_enrichment_summaries.Rd
BioPET/man/dcaData.Rd
BioPET/man/enrichment_simulation.Rd
BioPET/man/enrichment_analysis.Rd