nutrimouse: Nutrimouse dataset

In CCA: Canonical Correlation Analysis

Nutrimouse dataset

Description

The nutrimouse dataset comes from a nutrition study in the mouse. It was provided by Pascal Martin from the Toxicology and Pharmacology Laboratory (French National Institute for Agronomic Research).

Usage

data(nutrimouse)

Format

A list containing the following components:

• gene: data frame (40 * 120) with numerical variables

• lipid: data frame (40 * 21) with numerical variables

• diet: factor vector (40)

• genotype: factor vector (40)

Details

Two sets of variables were measured on 40 mice:

• expressions of 120 genes potentially involved in nutritional problems.

• concentrations of 21 hepatic fatty acids.

  The 40 mice were distributed in a 2-factors experimental design (4 replicates):

• Genotype (2-levels factor): wild-type and PPARalpha -/-

• Diet (5-levels factor): Oils used for experimental diets preparation were corn and colza oils (50/50) for a reference diet (REF), hydrogenated coconut oil for a saturated fatty acid diet (COC), sunflower oil for an Omega6 fatty acid-rich diet (SUN), linseed oil for an Omega3-rich diet (LIN) and corn/colza/enriched fish oils for the FISH diet (43/43/14).

Source

P. Martin, H. Guillou, F. Lasserre, S. Déjean, A. Lan, J-M. Pascussi, M. San Cristobal, P. Legrand, P. Besse, T. Pineau - Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study. Hepatology, in press, 2007.

References

www.inra.fr/internet/Centres/toulouse/pharmacologie/pharmaco-moleculaire/acceuil.html

Examples

data(nutrimouse)
boxplot(nutrimouse$lipid)

CCA documentation built on Sept. 8, 2023, 5:19 p.m.