CFAcoop: Colony Formation Assay: Taking into Account Cellular Cooperation

Cellular cooperation compromises the plating efficiency-based analysis of clonogenic survival data. This tool provides functions that enable a robust analysis of colony formation assay (CFA) data in presence or absence of cellular cooperation. The implemented method has been described in Brix et al. (2020). (Brix, N., Samaga, D., Hennel, R. et al. "The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation." Radiat Oncol 15, 248 (2020). <doi:10.1186/s13014-020-01697-y>) Power regression for parameter estimation, calculation of survival fractions, uncertainty analysis and plotting functions are provided.

Getting started

Package details

AuthorDaniel Samaga [cre, aut], Nikko Brix [aut], Kirsten Lauber [aut], Horst Zitzelsberger [aut]
MaintainerDaniel Samaga <>
Package repositoryView on CRAN
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CFAcoop documentation built on June 11, 2021, 5:14 p.m.