removeCovariate: Remove covariate from structural parameters in a model...

In Certara.RsNLME: Pharmacometric Modeling

Remove covariate from structural parameters in a model object.

Description

Remove one or more covariates from structural parameters in a model object.

Usage

removeCovariate(.Object, covariate = NULL, paramName = NULL)

Arguments

.Object	Model object
covariate	Covariates to remove from model. If NULL all covariates will be removed from model.
paramName	Structural parameters for which to remove covariate effect(s) from. If NULL covariate effect will be removed from all structural parameters.

Value

Modified NlmePmlModel object

Examples

model <- pkmodel(
  numCompartments = 2,
  data = pkData,
  ID = "Subject",
  Time = "Act_Time",
  A1 = "Amount",
  CObs = "Conc"
)

# Add Gender covariate of type categorical
model <- addCovariate(model,
  covariate = "Gender",
  type = "Categorical",
  effect = c("V2", "Cl2"),
  levels = c(0, 1),
  labels = c("Female", "Male")
)

# Add BodyWeight covariate of type continuous
model <- addCovariate(model,
  covariate = "BodyWeight",
  type = "Continuous",
  direction = "Backward",
  center = "Mean",
  effect = c("V", "Cl")
)

# Remove all covariates from model
model <- removeCovariate(model)

Certara.RsNLME documentation built on April 3, 2025, 11:04 p.m.