run_metamodel: Fit the NLME metamodel

In Certara.RsNLME: Pharmacometric Modeling

Fit the NLME metamodel

Description

Use for simple model execution given information contained in mmdl file.

Usage

run_metamodel(mmdlfile, directoryToRun, nlme_hostPath, host)

Arguments

mmdlfile	The metamodel file path; relative paths are acceptable.
directoryToRun	The directory where the final results should be stored If missing, the mmdlfile base directory is used.
nlme_hostPath	json file with host definition for model execution. Generated by Pirana application. Consider using host argument when running from R.
host	NlmeParallelHost() class instance.

Details

See Metamodel documentation.

If both nlme_hostPath and host specified, the former is used. If nlme_hostPath is missing, host is used instead. If both are missing, MPI local host with 4 threads is used for simple estimation mode, multicore host is used for the others.

Multiple ESTARGS/SIMARGS are supported, they are applied for the model sequentially, the results of previous estimation are applied to the model before the next one. ESTARGS queue is executed first, SIMARGS queue is executed the second.

Value

the results of fitmodel() run are returned if singular ESTARGS block is provided; otherwise a list of fitmodel() and simmodel() results are returned.

See Also

NlmeParallelHost, fitmodel

Examples

# path to metamodel should be specified
host <- hostParams(
  parallelMethod = "LOCAL_MPI",
  hostName = "local_mpi",
  numCores = 4
)
directoryToRun <- normalizePath("./NLME/")
run_metamodel("metamodel.mmdl", directoryToRun)

Certara.RsNLME documentation built on April 3, 2025, 11:04 p.m.