nb: Net Benefit

In ClinicalUtilityRecal: Recalibration Methods for Improved Clinical Utility of Risk Scores

Description

Estimates the net benefit and standardized net benefit of a risk score given a risk threshold R. Additionally estimates the standardized net benefit of a "treat-all" (everyone recieves intervention) treatment rule.

Usage

nb(y, p, r)

Arguments

y	Vector of binary outcomes, with 1 indicating event (case) and 0 indicating no event (controls)
p	Vector of risk score values
r	Clinically relevant risk threshold

Value

nb	Net benefit of risk score p
snb	Standardized net benefit of risk score p. Net benefit of p dived by the prevalence
snb.all	Standardized net benefit of a decision rule where everyone recieves treatment

Author(s)

Anu Mishra

References

Pauker, S. G., & Kassirer, J. P. (1980). The threshold approach to clinical decision making. New England Journal of Medicine, 302(20), 1109-1117.

Mishra, A. (2019). Methods for Risk Markers that Incorporate Clinical Utility (Doctoral dissertation). (Available Upon Request)

ClinicalUtilityRecal documentation built on April 17, 2020, 1:26 a.m.