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ComBatFamQC: Comprehensive Batch Effect Diagnostics and Harmonization
Provides a comprehensive framework for batch effect diagnostics, harmonization, and post-harmonization downstream analysis. Features include interactive visualization tools, robust statistical tests, and a range of harmonization techniques. Additionally, 'ComBatFamQC' enables the creation of life-span age trend plots with estimated age-adjusted centiles and facilitates the generation of covariate-corrected residuals for analytical purposes. Methods for harmonization are based on approaches described in Johnson et al., (2007) <doi:10.1093/biostatistics/kxj037>, Beer et al., (2020) <doi:10.1016/j.neuroimage.2020.117129>, Pomponio et al., (2020) <doi:10.1016/j.neuroimage.2019.116450>, and Chen et al., (2021) <doi:10.1002/hbm.25688>.
Getting started
Browse package contents
Package details |
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| Author | Zheng Ren [aut, cre, cph] (<https://orcid.org/0009-0006-2430-4625>), Andrew Chen [aut, cph] (<https://orcid.org/0000-0002-5027-6422>), Elizabeth Horwath [ctb] (<https://orcid.org/0009-0009-1224-6984>) |
| Maintainer | Zheng Ren <zren1422@gmail.com> |
| License | MIT + file LICENSE |
| Version | 1.0.6 |
| URL | https://github.com/Zheng206/ComBatFamQC https://zheng206.github.io/ComBatQC-Web/ |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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