# Developmental toxicology study of DEHP in mice

### Description

This data set is based on a National Toxicology Program study on diethylhexyl phthalate, DEHP. Pregnant CD-1 mice were randomly assigned to receive 0, 250, 500, 1000, or 1500 ppm of DEHP in their feed during gestational days 0-17. The uterine contents of the mice were examined for toxicity endpoints prior to normal delivery. The possible outcomes are 1) malformation, 2) death or resorption, 3) no adverse event.

### Usage

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### Format

A 'CMData' object, that is a data frame with the following variables

Trt | factor giving treatment group |

ClusterSize | the size of the litter |

NResp.1 | the number of fetuses with a type 1 outcome (malformation) |

NResp.2 | the number of fetuses with a type 2 outcome (death or resorption) |

NResp.3 | the number of fetuses with a type 3 outcome (normal) |

Freq | the number of litters with the given ClusterSize/NResp.1-NResp.3 combination |

### Source

National Toxicology Program, NTP Study TER84064.

### References

Tyl, R. W., Price, C. J., Marr, M. C., and Kimmel, C. A. (1988). Developmental toxicity evaluation of dietary
di(2-ethylhexy)phthalate in Fischer 344 rats and CD-1 mice. *Fundamental and Applied Toxicology*
10, 395-412.

### Examples

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