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Filter CpGs based on Intra-class Correlation Coefficients (ICCs) when replicates are available. ICCs are calculated by fitting linear mixed effects models to all samples including the un-replicated samples. Including the large number of un-replicated samples improves ICC estimates dramatically. The method accommodates any replicate design.
Package details |
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Author | Jun Chen <Chen.Jun2@mayo.edu> |
Maintainer | Jun Chen <chen.jun2@mayo.edu> |
License | GPL-3 |
Version | 1.1 |
Package repository | View on CRAN |
Installation |
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