CpGFilter: CpG Filtering Method Based on Intra-class Correlation Coefficients

Filter CpGs based on Intra-class Correlation Coefficients (ICCs) when replicates are available. ICCs are calculated by fitting linear mixed effects models to all samples including the un-replicated samples. Including the large number of un-replicated samples improves ICC estimates dramatically. The method accommodates any replicate design.

AuthorJun Chen
Date of publication2014-11-06 01:21:42
MaintainerJun Chen <chen.jun2@mayo.edu>

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