Description Usage Format References
Methotrexate is a drug used totreat cancer, but there is concern that it may itself be carcinogenic in healthy individuals who are exposed while either manufacturing or administering the drug. Deng et al. (2005) compared 21 workers engaged in the production of methotrexate to 21 unexp osed controls matched for age, gender, and smoking. The variables are (prefix "w" means exposed and "c" means control)
mutant frequency of TCR gene
mutant frequency of hprt gene
mean tail length
mean tail moment
identifier
sex
age
smoking
exposure years
protection measures, G for gloves, M for mask, N for none
if the protection includes mask
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A data.frame.
Deng, H., Zhang, M., He, J., Wu, W., Jin, L., Zheng, W., ... & Wang, B. (2005). Investigating genetic damage in workers occupationally exposed to methotrexate using three genetic end-points. Mutagenesis, 20(5), 351-357.
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