This package provides methods and examples to support a method of Gene Set Analysis (GSA). DBGSA is a novel distance-based gene set enrichment analysis method. We consider that, the distance between 2 groups with different phenotype by focusing on the gene expression should be larger, if a certain gene functional set was significantly associated with a particular phenotype.
|Author||Li Jin, Huang Meilin|
|Date of publication||2012-01-16 07:32:40|
|Maintainer||Li Jin <email@example.com>|
afExp: Gene expression profile
avelinkdis: Computing the distance by group average method
b1: Gene set function expression profile
centdis: Computing the distance by gravity method
DBGSA-package: methods of distance-based gene set functional enrichment...
distable: function to compute the specific distances between different...
distance: distances between case and control group
functionall: P values of distance-based gene set enrichment analysis
rand: distances of gene expression obtained by gene resampling
randdis: Randomly generating some gene expression profiles by gene...
valuep: function which computes p values from different phenotypes by...