R/deploid_utils.R

#' @keywords internal
"_PACKAGE"

#' Deconvolute Mixed Genomes with Unknown Proportions
#'
#' Traditional phasing programs are limited to diploid organisms.
#' Our method modifies Li and Stephens algorithm with Markov chain Monte Carlo
#' (MCMC) approaches, and builds a generic framework that allows haplotype
#' searches in a multiple infection setting. This package is primarily developed
#' as part of #' the Pf3k project, which is a global collaboration using the
#' latest sequencing technologies to provide a high-resolution view of natural
#' variation in the malaria parasite Plasmodium falciparum. Parasite DNA are
#' extracted from patient blood sample, which often contains more than one
#' parasite strain, with unknown proportions. This package is used for
#' deconvoluting mixed haplotypes, #' and reporting the mixture proportions from
#' each sample.
#'
#' @author
#' Joe Zhu
#'
#' Maintainer: Joe Zhu \email{sha.joe.zhu@gmail.com}
#'
#' @name DEploid.utils-package
#'
#' @importFrom Rcpp evalCpp
#' @importFrom scales alpha
#' @importFrom magrittr %>%
#' @importFrom utils read.table write.table
#' @importFrom stats cor cov quantile sd var
#' @importFrom graphics abline axis barplot hist image layout legend lines par points rect
#' @importFrom grDevices adjustcolor colorRampPalette dev.off heat.colors pdf png rainbow
#' @importFrom combinat permn
#' @useDynLib DEploid.utils, .registration = TRUE
NULL

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DEploid.utils documentation built on April 3, 2025, 9:58 p.m.