example_drug_target_list: An example data frame of drug target lists

In DTSEA: Drug Target Set Enrichment Analysis

An example data frame of drug target lists

Description

Drug-target interactions were downloaded and integrated from DrugBank and ChEMBL.

Usage

example_drug_target_list

Format

A data frame with 970 rows and 3 variables:

• drug_id: the DrugBank ID

• drug_name: the name of each drug

• gene_target: the targets of drugs

References

Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335.

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. doi: 10.1093/nar/gkw1074. Epub 2016 Nov 28. PMID: 27899562; PMCID: PMC5210557.

Examples

library(DTSEA)
data("example_drug_target_list", package = "DTSEA")

DTSEA documentation built on Nov. 10, 2022, 5:09 p.m.