Chen_2016_event_time: Function to generate event time in the existence of cured...

In EventPredInCure: Event Prediction Including Cured Population

Function to generate event time in the existence of cured population

Description

generate event time under the delay-treatment effect and cured population setting

Usage

Chen_2016_event_time(u, hr, distribution, p, lag, a, b, mu, sd)

Arguments

u	a scalar with between 0 and 1
hr	hazard ratio if this subject in the corresponding arm vs control arm
distribution	the distribution for the control arm, valid values of inputs include: exponential, weibull, log-normal, log-logistic
p	the proportion of cured population in the control arm
lag	delayed treatment effect time after treatment initialization, when the hr between treatment arm and control =1 until lag time
a	the shape parameter in the Weibull or the log-logistic distribution
b	the scale parameter in the exponential, Weibull or the log-logistic distribution
mu	the mean in the log-normal distribution
sd	the standard deviation in the log-normal distribution

Value

the event time

References

• Chen, Tai-Tsang. "Predicting analysis times in randomized clinical trials with cancer immunotherapy." BMC medical research methodology 16.1 (2016): 1-10.

EventPredInCure documentation built on May 29, 2024, 11:04 a.m.