Data on a set of flow cytometry experiments on signaling networks of human immune system cells. The dataset includes p=11 proteins and n=7466 samples.
dataHuman contains the following objects:
Matrix (7466x11) with the observations.
List of 5 matrices (1x11) each of which with a permutation of the nodes.
Matrix (11x11) with the adjacency matrix of the known regulatory network.
Sachs, K., Perez, O., Pe'er, D., Lauffenburger, D., and Nolan, G. (2003). Casual protein- signaling networks derived from multiparameter single-cell data. Science 308, 504-6.
D. Altomare, G. Consonni and L. La Rocca (2012). Objective Bayesian search of Gaussian directed acyclic graphical models for ordered variables with non-local priors. Article submitted to Biometric Methodology.
Shojaie, A. and Michailidis, G. (2010). Penalized likelihood methods for estimation of sparse high-dimensional directed acyclic graphs. Biometrika 97, 519-538.
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