Data set of an AIDS clinical trial

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Description

Data set from an AIDS clinical trial designed to study the benefits of Zidovudine therapy in patients in the early stage of HIV infection. It contains interval-censored data of 1607 individuals.

Usage

1

Format

A data frame with 1607 observations on the following 3 variables.

left

Left endpoint of censoring interval.

right

Right endpoint of censoring interval.

group

Treatment group (1=deferred therapy; 2=500 mg/day dosage; 3=1500 mg/day dosage).

References

Calle, M. L. and G<f3>mez, G. (2001). Nonparametric Bayesian estimation from interval-censored data using Monte Carlo methods. Journal of Statistical Planning and Inference 98, 73–87.

G<f3>mez, G., Calle, M. L. and Oller, R. (2004). Frequentist and Bayesian approaches for interval-censored data and their implementation in R. Statistical Papers 45, 139–173.

Volberding, P. A., Lagakos, S. W., Grimes, J. M., Stein, D. S., et al. (1995). A Comparison of Immediate with Deferred Zidovudine Therapy for Asymptomatic HIV-Infected Adults with CD4 Cell Counts of 500 or More per Cubic Millimeter. The New England Journal of Medicine 333, 401–407.