contrast.matrix: Construct Contrast Matrix

In FLASHMM: Fast and Scalable Single Cell Differential Expression Analysis using Mixed-Effects Models

Construct Contrast Matrix

Description

Construct the contrast matrix to make various comparsions of different treatments.

Usage

contrast.matrix(contrast, model.matrix.names)

Arguments

contrast	A vector of character strings specifying the various comparisons, which are the expressions constituted by model.matrix.names.
model.matrix.names	Column names of model (design) matrix.

Value

Matrix which columns correspond to contrasts.

Examples

model_variables <- c("A", "B", "C", "D")
contrast <- c("AvsB" = "A-B", "AvsC" = "A-C", 'AvsB.C.D'= "A-(B+C+D)/3")
contrast.matrix(contrast, model_variables)

FLASHMM documentation built on April 12, 2025, 1:32 a.m.