GEint: Misspecified Models for Gene-Environment Interaction

Compute the bias in misspecified linear gene-environment interaction models. The most generalized function for this objective is GE_bias(). However GE_bias() requires specification of many higher order moments of covariates in the model. If users are unsure about how to calculate/estimate these higher order moments, it may be easier to use GE_bias_normal_squaredmis(). This function places many more assumptions on the covariates (most notably that they are all jointly generated from a multivariate normal distribution) and is thus able to automatically calculate many of the higher order moments automatically, necessitating only that the user specify some covariances. There are also functions to solve for the bias through simulation and non-linear equation solvers, these can be used to check your work.

Author
Ryan Sun [aut, cre]
Date of publication
2016-10-01 01:07:46
Maintainer
Ryan Sun <ryansun.work@gmail.com>
License
GPL-3
Version
0.1.1

View on CRAN

Man pages

GE_bias
GE_bias.R
GE_bias_normal_squaredmis
GE_bias_normal_squaredmis.R
GE_BICS
GE_BICS.R
GE_enumerate_inputs
GE_enumerate_inputs.R
GE_nleqslv
GE_nleqslv #' Uses package nleqslv to get a numerical...
GE_scoreeq_sim
GE_scoreeq_sim.R
GE_test_moment_calcs
GE_test_moment_calcs.R
GE_translate_inputs
GE_translate_inputs.R

Files in this package

GEint
GEint/inst
GEint/inst/doc
GEint/inst/doc/GEint_example.Rmd
GEint/inst/doc/GEint_example.R
GEint/inst/doc/GEint_example.html
GEint/NAMESPACE
GEint/R
GEint/R/GE_nleqslv.R
GEint/R/GE_BICS.R
GEint/R/GE_bias_normal_squaredmis.R
GEint/R/GE_translate_inputs.R
GEint/R/GE_bias.R
GEint/R/GE_enumerate_inputs.R
GEint/R/GE_scoreeq_sim.R
GEint/R/GE_test_moment_calcs.R
GEint/vignettes
GEint/vignettes/GEint_example.Rmd
GEint/MD5
GEint/build
GEint/build/vignette.rds
GEint/DESCRIPTION
GEint/man
GEint/man/GE_bias.Rd
GEint/man/GE_test_moment_calcs.Rd
GEint/man/GE_nleqslv.Rd
GEint/man/GE_enumerate_inputs.Rd
GEint/man/GE_bias_normal_squaredmis.Rd
GEint/man/GE_BICS.Rd
GEint/man/GE_scoreeq_sim.Rd
GEint/man/GE_translate_inputs.Rd