clin_data: Example Clinical Dataset for T-cell Acute Lymphoblastic...

clin_dataR Documentation

Example Clinical Dataset for T-cell Acute Lymphoblastic Leukemia (T-ALL)

Description

This example dataset contains clinical and demographic information for 265 newly diagnosed T-cell Acute Lymphoblastic Leukemia (T-ALL) patients and is provided for demonstrating clinical and outcome analyses in GRIN2. The data originate from Liu, Yu, et al. (2017) and include variables describing patient characteristics, treatment response, and clinical outcomes.

Usage

clin_data

Format

A data frame with 265 rows and 11 columns:

ID

Unique patient identifier.

Sex

Patient sex.

Race

Patient race.

Age_Days

Age at diagnosis, in days.

WBC

White blood cell count at diagnosis.

MRD29

Measurable residual disease percentage at day 29 post-treatment.

MRD.binary

Binary MRD status (0 = MRD <= 0.1, 1 = MRD > 0.1).

os.time

Overall survival time in years from diagnosis to last follow-up or death.

os.censor

Overall survival event indicator (0 = censored/alive at last follow-up, 1 = death).

efs.time

Event-free survival time in years.

efs.censor

Event-free survival event indicator (0 = censored, 1 = event).

Source

Data derived from supplementary materials accompanying Liu, Yu, et al. (2017), Nature Genetics. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1038/ng.3909")}

Additional clinical variables were integrated from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) program: https://www.cancer.gov/ccg/research/genome-sequencing/target.


GRIN2 documentation built on Aug. 22, 2026, 5:09 p.m.