stage_1_selection: Stage 1-selection step of GSED
In GSED: Group Sequential Enrichment Design
stage_1_selection R Documentation
Stage 1-selection step of GSED
Description
stage_1_selection is used to determine the subgroup selected at the end of the first stage of GSED.
Usage
stage_1_selection(N_subsets, Z_1j, l, ordering, increasing_theta=FALSE)
Arguments
N_subsets
Integer representing the number of possible subgroups.
Z_1j
Vector containing the Z-statistics (standard normal under H0) for each subgroup. Must be of length N_subsets.
l
Vector containing the lower boundaries for stagewise decisions.
ordering
Boolean indicating if the subgroups (theta) are ordered.
increasing_theta
Boolean indicating if greater values of theta parameters represent better treatment effects. The default value is set at FALSE.
Value
A vector containing the indices of the subgroups selected is returned.
Author(s)
Marie-Karelle Riviere-Jourdan eldamjh@gmail.com
References
Baldur P. Magnusson and Bruce W. Turnbull. Group sequential enrichment design incorporating subgroup selection. Statistics in Medicine, 2013. <doi:10.1002/sim.5738>
Examples
stage_1_selection(N_subsets=3, Z_1j=c(-0.49,1.07,1.44), l=c(0.7962,2.5204), ordering=FALSE)
GSED documentation built on Aug. 31, 2023, 5:06 p.m.
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| stage_1_selection | R Documentation |
Stage 1-selection step of GSED
Description
stage_1_selection is used to determine the subgroup selected at the end of the first stage of GSED.
Usage
stage_1_selection(N_subsets, Z_1j, l, ordering, increasing_theta=FALSE)
Arguments
N_subsets |
Integer representing the number of possible subgroups. |
Z_1j |
Vector containing the Z-statistics (standard normal under H0) for each subgroup. Must be of length |
l |
Vector containing the lower boundaries for stagewise decisions. |
ordering |
Boolean indicating if the subgroups (theta) are ordered. |
increasing_theta |
Boolean indicating if greater values of theta parameters represent better treatment effects. The default value is set at FALSE. |
Value
A vector containing the indices of the subgroups selected is returned.
Author(s)
Marie-Karelle Riviere-Jourdan eldamjh@gmail.com
References
Baldur P. Magnusson and Bruce W. Turnbull. Group sequential enrichment design incorporating subgroup selection. Statistics in Medicine, 2013. <doi:10.1002/sim.5738>
Examples
stage_1_selection(N_subsets=3, Z_1j=c(-0.49,1.07,1.44), l=c(0.7962,2.5204), ordering=FALSE)
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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