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Code
summary(JointFPM(Surv(time = start, time2 = stop, event = event, type = "counting") ~
1, re_model = ~ pyridoxine + thiotepa, ce_model = ~ pyridoxine + thiotepa,
re_indicator = "re", ce_indicator = "ce", df_ce = 3, df_re = 3, cluster = "id",
data = bladder1_stacked))
Output
Coefficients CE model --------------------------------------------------------------------
Estimate Std. Error z value Pr(z)
(Intercept) -4.66109572 0.6172954 -7.5508351 4.324762e-14
pyridoxine -0.04122802 0.4950614 -0.0832786 9.336300e-01
thiotepa 0.25721226 0.4192089 0.6135658 5.395023e-01
nsx(log(stop), 3)1 2.35314415 0.5439871 4.3257354 1.520238e-05
nsx(log(stop), 3)2 4.88863017 0.6698078 7.2985569 2.908705e-13
nsx(log(stop), 3)3 3.03025917 0.5047027 6.0040473 1.924586e-09
Coefficients RE model --------------------------------------------------------------------
Estimate Std. Error z value Pr(z)
(Intercept) -3.37345897 0.2634091 -12.80691692 1.499759e-37
pyridoxine 0.01259029 0.3129425 0.04023196 9.679082e-01
thiotepa -0.40373220 0.2872148 -1.40568047 1.598190e-01
nsx(log(stop), 3)1 2.95784540 0.2202084 13.43202892 3.925081e-41
nsx(log(stop), 3)2 6.56717183 0.4002125 16.40921356 1.643201e-60
nsx(log(stop), 3)3 3.07195562 0.1886666 16.28245729 1.314815e-59
-2 Log-likelihood: -1831.05
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