unanchored_maic: Conduct non-Anchored Matching-Adjusted Indirect Comparison...

In MAICtools: Performing Matched-Adjusted Indirect Comparisons (MAIC)

Conduct non-Anchored Matching-Adjusted Indirect Comparison (MAIC).

Description

Conduct non-Anchored Matching-Adjusted Indirect Comparison (MAIC).

Arguments

unds_wts	A combined data frame containing individual efficacy data from the intervention study and pseudo efficacy data from the comparator study.
unds.arm	The name of the grouping column in the combined data frame specified by unds_wts, e.g., comparator.arm = TRT. The default is TRT.
comparator.study	A character specifying or presenting the comparator study, e.g., comparator.study = "Study XX-1".
unds.param.var	The name of the column that specifies only a subset of the rows of the data to be used.
unds.param	A character specifying the subset of the rows to be used. This is the value of the column set by the unds.param.var.
time	The name of the survival or follow up time column in the combined data frame.
status	The status indicator, normally 0 = event, 1 = censored. Can be reseted using the event parameter.
event	A numeric value that represents the survival status, 0 = event, 1 = censored.
response	The name of the response status column in the unds_wts.
dtype	Two options are available: "HR" and "OR". The default is "HR".
wt.col	The name of the estimated weights column in the data frame specified by unds_wts. The default is wt.
CIw	The numeric value specifying the width of the confidence interval, with a default of 0.95.
digits	Specify the number of decimal places for the output results.

Value

A data frame containing the non-anchored matching-adjusted indirect comparison results.

Examples

results3 <- unanchored_maic(
  unds_wts = unpts, unds.arm = ARM,
  comparator.study = "Study XX-1",
  unds.param.var = PARAMCD, unds.param = "OS",
  time = AVAL, status = CNSR, event = 0,
  dtype = "HR")

results3

results4 <- unanchored_maic(
  unds_wts = unpts, unds.arm = ARM,
  #' unds.param = "ORR",
  #' comparator.study = "Study XX-1",
  response = CNSR,
  dtype = "OR")

results4

MAICtools documentation built on April 4, 2025, 12:17 a.m.