psoriasis90: Studies of biologics for treatment of moderate-to-severe...

In MBNMAdose: Dose-Response MBNMA Models

Studies of biologics for treatment of moderate-to-severe psoriasis (>=90% improvement)

Description

A dataset from a systematic review of Randomised-Controlled Trials (RCTs) comparing biologics at different doses and placebo \insertCitewarren2019MBNMAdose. The outcome is the number of patients experiencing >=90% improvement on the Psoriasis Area and Severity Index (PASI) measured at 12 weeks follow-up. The dataset includes 24 Randomised-Controlled Trials (RCTs), comparing 9 different biologics at different doses with placebo.

Usage

psoriasis90

Format

A data frame in long format (one row per arm and study), with 81 rows and 9 variables:

• studyID Study identifiers

• agent Character data indicating the agent to which participants were randomised

• dose_mg Numeric data indicating the dose to which participants were randomised in mg

• freq Character data indicating the frequency of the dose to which participants were randomised

• dose Numeric data indicating the dose in mg/week to which the participants were randomised

• n Numeric data indicating the number of participants randomised

• r Numeric data indicating the number of participants who achieved >=90% improvement in PASI score after 12 weeks

References

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MBNMAdose documentation built on Aug. 8, 2023, 5:11 p.m.