ssri: Studies of Selective Serotonin Reuptake Inhibitors (SSRIs)...

In MBNMAdose: Dose-Response MBNMA Models

Studies of Selective Serotonin Reuptake Inhibitors (SSRIs) for major depression

Description

A dataset from a systematic review examining the efficacy of different doses of SSRI antidepressant drugs and placebo \insertCitefurukawa2019MBNMAdose. The response to treatment is defined as a 50% reduction in depressive symptoms after 8 weeks (4-12 week range) follow-up. The dataset includes 60 RCTs comparing 5 different SSRIs with placebo.

Usage

ssri

Format

A data frame in long format (one row per arm and study), with 145 rows and 8 variables:

• studyID Study identifiers

• bias Risk of bias evaluated on 6 domains

• age Mean participant age

• weeks Duration of study follow-up

• agent Character data indicating the agent to which participants were randomised

• dose Numeric data indicating the dose to which participants were randomised in mg

• n Numeric data indicating the number of participants randomised

• r Numeric data indicating the number of participants who achieved >50% improvement in depression symptoms

References

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MBNMAdose documentation built on Aug. 8, 2023, 5:11 p.m.