A dataset from a systematic review examining the efficacy of different doses of SSRI antidepressant drugs and placebo \insertCitefurukawa2019MBNMAdose. The response to treatment is defined as a 50% reduction in depressive symptoms after 8 weeks (4-12 week range) follow-up. The dataset includes 60 RCTs comparing 5 different SSRIs with placebo.
A data frame in long format (one row per arm and study), with 145 rows and 8 variables:
studyID Study identifiers
bias Risk of bias evaluated on 6 domains
age Mean participant age
weeks Duration of study follow-up
agent Character data indicating the agent to which participants were randomised
dose Numeric data indicating the dose to which participants were randomised in mg
N Numeric data indicating the number of participants randomised
r Numeric data indicating the number of participants who achieved >50% improvement in depression symptoms
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