MPBoost-package: Treatment Allocation in Clinical Trials by the Maximal...

Description Details Author(s) References


Performs treatment allocation in two-arm clinical trials by the maximal procedure described by Berger et al. (2003) <doi:10.1002/sim.1538>. To that end, the algorithm provided by Salama et al. (2008) <doi:10.1002/sim.3014> is implemented.


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Ignacio López-de-Ullibarri

Maintainer: Ignacio López-de-Ullibarri <>


Berger, V. W., Ivanova, A., Knoll, M. D. (2003). Minimizing predictability while retaining balance through the use of less restrictive randomization procedures. Statistics in Medicine, 22: 3017-3028. doi: 10.1002/sim.1538.

Salama, I., Ivanova, A., Qaqish, B. (2008). Efficient generation of constrained block allocation sequences. Statistics in Medicine, 27, 1421-1428. doi: 10.1002/sim.3014.

MPBoost documentation built on Oct. 6, 2021, 9:06 a.m.