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A causal mediation approach under the counterfactual framework to test the significance of total, direct and indirect effects. In this approach, a group of methylated sites from a predefined region are utilized as the mediator, and the functional transformation is used to reduce the possible high dimension in the region-based methylated sites and account for their location information.
Package details |
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Author | Qi Yan |
Maintainer | Qi Yan <qy2253@cumc.columbia.edu> |
License | GPL (>= 2) |
Version | 1.0.1 |
Package repository | View on CRAN |
Installation |
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