Description Usage Arguments Value Author(s) Examples
This function allows you to calculate the score summary statistics U and their covariance matrix V for MTAR, given the score summary statistics and their variance.
1 | Get_UV_from_varU(U, varU, R)
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U |
a numeric list, each sublist containing score summary statistics U for each study. In each study, a numeric m \times K matrix with each row as a SNP and each column as a separate trait. The number of traits and the number of SNPs in each study can be different but their names are required. |
varU |
a numeric list, each sublist containing the variance of score summary statistics information for each study. In each study, a numeric m \times K matrix with each row as a SNP and each column as a separate trait. |
R |
a SNP correlation matrix, which should contain the correlation of all the SNPs in these studies. |
A list containing summary statistics for each traits, the score summary statistics U and their covariance matrix V.
Lan Luo
1 2 3 4 5 | data("varU.example")
attach(varU.example)
obs.stat <- Get_UV_from_varU(U = U, varU = varU, R= R)
obs.stat
detach(varU.example)
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