# MVR: Mean-Variance Regularization

This is a non-parametric method for joint adaptive mean-variance regularization and variance stabilization of high-dimensional data. It is suited for handling difficult problems posed by high-dimensional multivariate datasets (p >> n paradigm). Among those are that the variance is often a function of the mean, variable-specific estimators of variances are not reliable, and tests statistics have low powers due to a lack of degrees of freedom. Key features include: (i) Normalization and/or variance stabilization of the data, (ii) Computation of mean-variance-regularized t-statistics (F-statistics to follow), (iii) Generation of diverse diagnostic plots, (iv) Computationally efficient implementation using C/C++ interfacing and an option for parallel computing to enjoy a faster and easier experience in the R environment.

- Author
- Jean-Eudes Dazard [aut, cre], Hua Xu [ctb], Alberto Santana [ctb]
- Date of publication
- 2016-10-26 00:18:37
- Maintainer
- Jean-Eudes Dazard <jean-eudes.dazard@case.edu>
- License
- GPL (>= 3) | file LICENSE
- Version
- 1.31.0
- URLs

## Man pages

- cluster.diagnostic
- Function for Plotting Summary Cluster Diagnostic Plots
- mvr
- Function for Mean-Variance Regularization and Variance...
- MVR.news
- Function to Display the NEWS File
- MVR-package
- Mean-Variance Regularization Package
- mvrt.test
- Function for Computing Mean-Variance Regularized T-test...
- normalization.diagnostic
- Function for Plotting Summary Normalization Diagnostic Plots
- Real-data
- Real Proteomics Dataset
- stabilization.diagnostic
- Function for Plotting Summary Variance Stabilization...
- Synthetic-data
- Multi-Groups Synthetic Dataset
- target.diagnostic
- Function for Plotting Summary Target Moments Diagnostic Plots

## Files in this package

MVR |

MVR/inst |

MVR/inst/CITATION |

MVR/inst/NEWS |

MVR/inst/doc |

MVR/inst/doc/MVR_1.31.0.pdf |

MVR/src |

MVR/src/MVRc.cpp |

MVR/src/MVRc.h |

MVR/NAMESPACE |

MVR/data |

MVR/data/Synthetic.rda |

MVR/data/Real.rda |

MVR/R |

MVR/R/MVRr.internal.r |

MVR/R/MVRr.r |

MVR/MD5 |

MVR/DESCRIPTION |

MVR/man |

MVR/man/stabilization.diagnostic.Rd |

MVR/man/Synthetic-data.Rd |

MVR/man/MVR-package.Rd |

MVR/man/cluster.diagnostic.Rd |

MVR/man/MVR.news.Rd |

MVR/man/normalization.diagnostic.Rd |

MVR/man/mvrt.test.Rd |

MVR/man/mvr.Rd |

MVR/man/target.diagnostic.Rd |

MVR/man/Real-data.Rd |

MVR/LICENSE |