This is a non-parametric method for joint adaptive mean-variance regularization and variance stabilization of high-dimensional data. It is suited for handling difficult problems posed by high-dimensional multivariate datasets (p >> n paradigm). Among those are that the variance is often a function of the mean, variable-specific estimators of variances are not reliable, and tests statistics have low powers due to a lack of degrees of freedom. Key features include: (i) Normalization and/or variance stabilization of the data, (ii) Computation of mean-variance-regularized t-statistics (F-statistics to follow), (iii) Generation of diverse diagnostic plots, (iv) Computationally efficient implementation using C/C++ interfacing and an option for parallel computing to enjoy a faster and easier experience in the R environment.
|Author||Jean-Eudes Dazard [aut, cre], Hua Xu [ctb], Alberto Santana [ctb]|
|Date of publication||2016-10-26 00:18:37|
|Maintainer||Jean-Eudes Dazard <firstname.lastname@example.org>|
|License||GPL (>= 3) | file LICENSE|
cluster.diagnostic: Function for Plotting Summary Cluster Diagnostic Plots
mvr: Function for Mean-Variance Regularization and Variance...
MVR.news: Function to Display the NEWS File
MVR-package: Mean-Variance Regularization Package
mvrt.test: Function for Computing Mean-Variance Regularized T-test...
normalization.diagnostic: Function for Plotting Summary Normalization Diagnostic Plots
Real-data: Real Proteomics Dataset
stabilization.diagnostic: Function for Plotting Summary Variance Stabilization...
Synthetic-data: Multi-Groups Synthetic Dataset
target.diagnostic: Function for Plotting Summary Target Moments Diagnostic Plots