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The nonparametric two-stage Bayesian adaptive design is a novel phase II clinical trial design for finding the minimum effective dose (MinED). This design is motivated by the top priority and concern of clinicians when testing a new drug, which is to effectively treat patients and minimize the chance of exposing them to subtherapeutic or overly toxic doses. It is used to design single-agent trials.
Package details |
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Author | Chia-Wei Hsu, Fang Wang, Rongji Mu, Haitao Pan, Guoying Xu |
Maintainer | Chia-Wei Hsu <Chia-Wei.Hsu@stjude.org> |
License | GPL-2 |
Version | 0.1.3 |
Package repository | View on CRAN |
Installation |
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