NPHMC | R Documentation |
Title
NPHMC( n = NULL, power = 0.8, alpha = 0.05, accrualtime = NULL, followuptime = NULL, p = 0.5, accrualdist = c("uniform", "increasing", "decreasing"), hazardratio = NULL, oddsratio = NULL, pi0 = NULL, survdist = c("exp", "weib"), k = 1, lambda0 = NULL, data = NULL )
n |
sample size needed for power calculation |
power |
powered needed for sample size calculation |
alpha |
level of significance of statistical test (default is 0.05) |
accrualtime |
level of accrual period |
followuptime |
length of follow up time |
p |
proportion of subjects in treatment arm (default is 0.5) |
accrualdist |
accrual pattern (uniform, decreasing, increasing) |
hazardratio |
hazard ratio of uncured patients between two arms (must be greater than 0) |
oddsratio |
odds ratio of cured patients between two arms. It must be greater than 0. If it is 0, the model is reduced to standard proportional hazards model. |
pi0 |
cure rate for the control arm (between 0 and 1) |
survdist |
distribution of uncured patients ( |
k |
shape parameter if survdist = 'weib' (By default, it is 1 referrring to exponential distribution) |
lambda0 |
scale parameter of exponential or Weibull distribution for survival times of uncured patients in the control arm. |
data |
observed or historical data if available |
a NPHMC object
NPHMC(power=0.90,alpha=0.05,accrualtime=3,followuptime=4,p=0.5,accrualdist="uniform", hazardratio=2/2.5,oddsratio=2.25,pi0=0.1,survdist="exp",k=1,lambda0=0.5) data(e1684szdata) NPHMC(power=0.80,alpha=0.05,accrualtime=4,followuptime=3,p=0.5,accrualdist="uniform", data=e1684szdata) n=seq(100, 500, by=50) NPHMC(n=n, alpha=0.05,accrualtime=3,followuptime=4,p=0.5, accrualdist="uniform", hazardratio=2/2.5,oddsratio=2.25,pi0=0.1,survdist="exp", k=1,lambda0=0.5) n=seq(100, 500, by=50) NPHMC(n=n,alpha=0.05,accrualtime=4,followuptime=3,p=0.5, accrualdist="uniform",data=e1684szdata)
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.