alzheimers_biomarkers_tbl_df: Alzheimer's Disease Biomarkers Study

In NeuroDataSets: A Comprehensive Collection of Neuroscience and Brain-Related Datasets

Alzheimer's Disease Biomarkers Study

Description

This dataset, alzheimers_biomarkers_tbl_df, is a tibble containing clinical data from 333 patients in a study of Alzheimer's disease biomarkers. The study included patients with mild cognitive impairment and healthy controls, with measurements of demographic characteristics, apolipoprotein E genotype, protein biomarkers (including Abeta, Tau, and pTau), and clinical dementia scores.

Usage

data(alzheimers_biomarkers_tbl_df)

Format

A tibble with 333 observations and 131 variables:

age

Numeric: Patient age

male

Numeric: Indicator for male gender (1 = male, 0 = female)

Genotype

Factor: Apolipoprotein E genotype

Class

Factor: Clinical classification (e.g., healthy, impaired)

Ab_42

Numeric: Amyloid-beta 42 protein measurement

tau

Numeric: Tau protein measurement

p_tau

Numeric: Phosphorylated Tau protein measurement

[131 additional biomarker variables]

Numeric measurements of various proteins and biomarkers

Details

The dataset name has been kept as 'alzheimers_biomarkers_tbl_df' to avoid confusion with other datasets in the R ecosystem. This naming convention helps distinguish this dataset as part of the NeuroDataSets package. The suffix 'tbl_df' indicates that the dataset is a tibble. The original content has not been modified.

Source

Data taken from the modeldata package version 1.4.0. Original study: Craig-Schapiro R, Kuhn M, Xiong C, et al. (2011) Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis. PLoS ONE 6(4): e18850.

NeuroDataSets documentation built on June 8, 2025, 11:46 a.m.